Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases. A long-term follow-up study of survival in stage I (T1N0M0) and stage II (T1N1M0) breast carcinoma. Rosen PR, Groshen S, Saigo PE, Kinne DW, Hellman S.Prognosis of nonpalpable infiltrating carcinoma of the breast. Ciatto S, Cecchini S, Iossa A, Grazzini G, Bravetti P, Rosselli del Turco M, Cataliotti L, Cardona G, Bianchi S.Management of nonpalpable breast abnormalities. Papatestas AE, Hermann D, Hermann G, Tsevdos C, Lesnick G.Significance and staging of nonpalpable carcinomas of the breast. Treatment and survival of female patients with nonpalpable breast carcinoma. Tinnemans JG, Wobbes T, Holland R, Hendriks JH, Van der Sluis RF, De Boer HH.Variation in the benign to malignant ratio. Predicting the risk of cancer at the time of breast biopsy. Spivey GH, Perry BW, Clark VA, Coulson AH, Coulson WF.Changing patterns during a five-year period. Lay SF, Crump JM, Frykberg ER, Goedde TA, Copeland EM., 3rd Breast biopsy.Thompson RS, Taplin SH, Carter AP, Schnitzer F.Progress in early breast cancer detection. Survival experience in the Breast Cancer Detection Demonstration Project. Seidman H, Gelb SK, Silverberg E, LaVerda N, Lubera JA.Experience with mammography in a tumor institution. Technique and guidelines for needle localization biopsy of nonpalpable lesions of the breast. Links to PubMed are also available for Selected References. Get a printable copy (PDF file) of the complete article (719K), or click on a page image below to browse page by page. Full textįull text is available as a scanned copy of the original print version. These findings emphasize the benefit of early detection of breast cancer through the use of mammography. For those with negative or unknown nodes, the disease-free survival rate is 98% (67 of 68 patients). Six of seven recurrences occurred in node-positive patients. Disease-free survival rate is 92% (79 of 86 patients) and overall survival rate is 94% (81 of 86 patients). Overall 18 of 78 lesions (23%) had positive nodes. Nodal status is unknown for eight patients. Twenty-eight of eighty-six lesions (32%) measured more than 1.0 cm with 8 of 28 (28%) positive nodes. Thirty-nine of eighty-six lesions (46%) measured 0.6 to 1.0 cm with 10 (26%) positive nodes. Division of the tumors into size with nodal status revealed 19 of 86 lesions (22%) less than 0.5 cm with 0 of 14 positive nodes. Mastectomy was performed in 71 of 86 lesions (82%), lumpectomy/radiation in 14 of 86 (16%), and lumpectomy alone in 1 of 86 lesions. Histologic subtypes were infiltrating ductal (63 of 86), infiltrating lobular (14 of 86), and other infiltrating (9 of 86). Mammographic findings leading to biopsy were a mass in 61 of 86 cases (71%), microcalcifications in 23 of 86 (27%), or both in 2 of 86 cases. Invasive cancer (86 of 264 lesions or 33%) forms the basis for this report. One hundred seventy-eight of these (67%) were in situ lesions. Two hundred sixty-four cancerous lesions (18%) were found. The use of mammography has resulted in 1464 breast biopsies for nonpalpable abnormalities at the University of Virginia in the 10 years 1980 to 1989.
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